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Dear colleagues,

It gives great pleasure to invite you to the First European Pulmonary Embolism Response Expertise Conference (EXPERT) in Leiden, the Netherlands: EXPERT-PE 2022.

The organizing committee of EXPERT-PE 2022 has set the dates at 15-16 October 2022.

EXPERT-PE 2022 is dedicated to increase knowledge on the best practice, multidisciplinary, initial and chronic management of acute severe pulmonary embolism.

The field of acute pulmonary embolism has seen an impressive evolution in recent years. Interventional treatment as well as novel antithrombotic strategies have considerably changed the treatment of acute pulmonary embolism, and extensive research is ongoing into the optimal use of existing treatment modalities in individual patients.

The program for the upcoming EXPERT-PE conference covers many aspects of the disease, with an overall focus on a multidisciplinary approach, ranging from diagnosis to interventional treatment, medical and multimodal therapy.

Our goal is to offer a platform for sharing and discussing the latest scientifi c and clinical developments in severe pulmonary embolism, and we will enable an informative and dynamic conference.

The conference is designed for practicing clinicians, who regularly care for patients with acute pulmonary embolism, and we thus welcome (interventional) cardiologists, pulmonologists, intensivists, vascular medicine specialists, haematologists, angiologists, and (interventional) radiologists.

In 2022, Leiden is the European City of Science. Leiden2022 will host a 365-day science festival of which EXPERT-PE is a proud partner. There was never a better time to visit Leiden and the Netherlands!

We look forward to welcoming you to Leiden.





Professor Menno Huisman
Chair EXPERT-PE conference 2022
Leiden University Medical Center



Professor Stavros Konstantinides
Co-Chair EXPERT-PE conference 2022
Center for Thrombosis and Hemostasis (CTH)
Johannes Gutenberg University Mainz




Dr Erik Klok
Chair Scientific Committee EXPERT-PE conference 2022
Leiden University Medical Center



We aim to meet you all in person. However, in view of the then current COVID-19 situation, we will adapt the meeting in accordance with restrictions/regulations relevant in October 2022.


Program

Program October 15th – 16th, 2022

  Saturday 15th October 2022
08.00 - 09.00  Registration 
  Opening 
09.00 - 09.10 Welcome by chairs
Menno Huisman, internist-vascular medicine, Leiden University Medical Center, the Netherlands
Stavros Konstantinides, cardiologist, University Medical Center Mainz, Germany
Erik Klok, internist-vascular medicine, Leiden University Medical Center, the Netherlands

09.10 - 09.30 Introduction into severe pulmonary embolism (PE) - magnitude of the problem
Stefano Barco, internist and vascular medicine specialist, University Hospital Zürich, Switzerland
  Session 1 - Diagnosis of acute PE
09.30 - 09.50 Diagnosis of acute PE in unstable patients
Lukas Hobohm, internist, University Medical Center Mainz, Germany

09.50 - 10.10 Diagnosis of acute PE in 2022 in special populations
Fionnuala Ni Ainle, haematologist, Mater Misericordiae University Hospital, Dublin, Ireland

10.10 - 10.30  Innovative imaging of acute PE
Deepa Gopalan, cardiovascular radiologist, Imperial College, London, United Kingdom

10.30 - 11.00 Break
  Session 2 - Case discussions
11.00 - 11.30 Case discussion - EXPERT-PE team Mannheim
Daniel Dürschmied, cardiologist, University Hospital Mannheim, Germany

11.30 - 12.00 Case discussion - EXPERT-PE team Cardiff
Andrew Sharp, cardiologist, University Hospital of Wales, Cardiff, United Kingdom

12.00 - 13.30 Lunch
  Session 3 - Treatment of acute PE
13.30 - 13.45 How to define acute PE patients
Stavros Konstantinides, cardiologist, University Medical Center Mainz, Germany

13.45 - 14.15 Treatment of acute high-risk PE
Nicolas Meneveau, cardiologist, University of Franche-Comté, Besançon, France

14.15 - 14.30 Rescue treatment after failure of thrombolysis
Jose Montero Cabezas, cardiologist, Leiden University Medical Center, the Netherlands
  Session 4 - Top research
14.30 - 14.45 Translation from right ventricular dysfunction to clinic
Harm Jan Bogaard, pulmonologist, Amsterdam University Medical Center, the Netherlands

14.15- 15.00 Treatment of acute PE with reduced-dose thrombolysis
Olivier Sanchez, pulmonologist, Georges Pompidou European Hospital, Paris, France

15.00 - 16.00 Break

16.00 - 17.00 Session 5 - Science abstract presentations and posters
  Chairs: Olivier Sanchez and Harm Jan Bogaard
17.00 - 18.00 Parallel session 6 - Workshops
  Workshop 1 - How to build an EXPERT-PE team
Menno Huisman, Erik Klok, Jose Montero Cabezas, Elzo Kraemer PE-ALERT team Leiden University Medical Center, the Netherlands

  Workshop 2 - How to manage bleeding in the severe PE patient
Jeroen Eikenboom, internist-vascular medicine/haematology, Leiden University Medical Center, the Netherlands

  Cécile Tromeur, pulmonologist, Brest University Hospital, France

  Workshop 3 - Point of care cardiac ultrasound in severe PE
Miriam Puls, cardiologist, University Medical Center Göttingen, Germany
18.00 - 18.30 Session 7 - Debate “Optimal place for a severe PE patient”
  Chairs: Piotr Pruszczyk and Laurent Bertoletti

Should all severe PE patients be referred to an expert center?
Pro: Adriaan Kraaijeveld, cardiologist, UMC Utrecht, the Netherlands

Con: Irene Lang, cardiologist, University Hospital Vienna, Austria

18.30 - 18.35 Wrap-up and closure first day
Menno Huisman
Stavros Konstantinides
Erik Klok
  Sunday 16th October 2022
08.30 - 09.30 Registration
  Session 8 - Post acute PE
09.30 - 09.50 Post PE syndrome – definition and implications
Erik Klok, internist-vascular medicine, Leiden University Medical Center, the Netherlands

09.50 - 10.10 Re-imaging – when is it indicated after severe PE?
Lilian Meijboom, radiologist, Amsterdam University Medical Center, the Netherlands

10.10 - 10.30 Antithrombotic treatment in severe PE
Menno Huisman, internist-vascular medicine, Leiden University Medical Center, the Netherlands

10.30 - 11.30 Break
11.30 - 12.15 Session 9 - Debate “Optimal reperfusion technique in severe PE”
  Chair: Olivier Sanchez

Catheter-directed thrombus removal is the best option
Ingo Ahrens, cardiologist, Augustinerinnen Hospital, Cologne, Germany

Systemic thrombolysis is the best option
Peter Verhamme, internist-vascular medicine, University Hospital Leuven, Belgium
  Closing
12.15 - 12.45 Farewell remarks
Menno Huisman
Stavros Konstantinides
Erik Klok

     

   

 

Accreditation


An application has been made to the UEMS EACCME® for CME accreditation of this event.

  • Accreditation of this course is requested from the Dutch Society of Internal Medicine
  • Accreditation of this course is requested from the Dutch Society of Pulmonology and Tuberculosis
  • Accreditation of this course is requested from The Netherlands Society of Cardiology
  • Accreditation of this course is requested from the Dutch Society of Radiology
  • ABIC








   

 

EXPERT-PE


The field of acute pulmonary embolism has seen an impressive evolution in recent years. Interventional treatment as well as novel antithrombotic strategies have considerably changed the treatment of acute pulmonary embolism, and extensive research is ongoing into the optimal use of existing treatment modalities in individual patients.

EXPERT- PE is an independent, not-for-profit, network of multidisciplinary academic and non-academic clinicians. We are dedicated to increase knowledge on the best practice of initial and chronic management of acute severe pulmonary embolism.

We have two main goals, i.e. education and accreditation.

  • We will disseminate education by organizing workshops and conferences in which we share and discuss the latest scientific and clinical developments in severe pulmonary embolism
  • We aim to organize accreditation for interested hospitals with multidisciplinary pulmonary embolism teams to become EXPERT-PE centers.

   

 

Abstracts


Coming soon.












   

 

Faculty




Prof. Harm Jan Bogaard
Harm Jan Bogaard is a pulmonologist and professor of experimental pulmonary medicine at the Amsterdam University Medical Centers. He is research director of the department of Pulmonary Medicine and co-director of Amsterdam cardiovascular sciences. He leads two research consortia of the Dutch Cardiovascular Alliance: DOLPHIN and PHAEDRA-IMPACT These consortia unite basic and translational scientists with clinical scientists devoted to cardiovascular research and care of patients with pulmonary hypertension, including chronic thromboembolic pulmonary hypertension. Prof. Bogaard co-founded the OPTICS consortium, which is a national consortium of the Amsterdam University Medical Centers expert center for Pulmonary hypertension together with a number of community hospitals involved in the care for patients with pulmonary hypertension. In the consortia, patient registries and materials are shared according to the highest standards of data management. Focus areas are advanced imaging (PET, MRI), animal models of disease and organ on chip approaches. Prof. Bogaard collaborates with a number of international research groups, including leading PH groups in Paris (France), Giessen (Germany), Stanford (USA) and Quebec (Canada).





Dr. Stefano Barco
Stefano Barco is an internist and vascular medicine specialist working as staff physician and head of research at the Department of Angiology of the University Hospital Zurich, Switzerland. He is active in the acute and long-term care of patients with pulmonary embolism, also including novel endovascular strategies. He has written or co-authored 150 articles in peer-reviewed journals primarily focusing on the epidemiology and management of pulmonary embolism. He is a member of the World Thrombosis Day steering committee, in the nucleus of the European Society of Cardiology "Working Group on Pulmonary Circulation and Right Ventricular Function", co-chair of the International Society on Thrombosis and Hemostasis subcommittee "Factor XI and the Contact System", and has editorial duties in several scientific journals in the field.





Dr. Laurent Bertoletti
Laurent Bertoletti is Medical Doctor and Professor of Medicine in the University Hospital of St-Etienne (CHUSE), France. He graduated as a chest physician in the faculty of Medicine of St-Etienne, France. After a fellowship in the department of Pr Gerald SIMONNEAU (Paris), he created and developed the pulmonary hypertension program of the University Hospital of St-Etienne. After a post-doc in the "Angiology and Haemostasis" department of Pr H BOUNAMEAUX (Geneva, Switzerland), he moved to the Vascular Medicine department of the CHUSE, the department he leads for several years.
His current researches focus on the management of vascular diseases, with specific attention to anticoagulant therapy in patients with pulmonary vascular diseases. He is highly involved in clinical research in venous thromboembolism, with interaction in basic sciences He is the national coordinator of the RIETE registry, and the co-coordinator of the French INNOVTE network (with Pr Francis COUTURAUD, Brest, France).
In 2021, he has been elected chairman of the "Pulmonary Embolism" sub-assemble of the European Respiratory Society, a large scientific society, which spans over 160 countries, prioritizing science, education and advocacy to promote lung health. He authored more than 250 references on Pubmed.





Prof. Jeroen Eikenboom
Jeroen Eikenboom received his MD degree in 1988 at the Erasmus University Rotterdam and his PhD at the Leiden University in 1994. He was trained in internal medicine at the Leiden University Medical Centre and sub-specialized in haematology and vascular medicine. He is professor of Internal Medicine/Haemostasis and Thrombosis since 2011. His clinical work is focused on bleeding disorders, thrombophilia and vascular medicine. His research is focused especially on bleeding and bleeding disorders.





Daniel Duerschmied, MD, FESC
Medical School Ulm, Germany, and Paris, France, 1997-2004. MD thesis 2004 (summa cum laude, with Guido Adler). 2004-2021 physician scientist, Cardiology and Angiology I, Heart Center Freiburg - Bad Krozingen, and Medical Intensive Care, Medical Center, University of Freiburg, Germany (with Christoph Bode). Post-doctoral research fellow, Harvard Medical School, Boston, USA, 2007-2009 (with Denisa Wagner). Since October 2021 Director of the Department of Cardiology, Angiology, Haemostaseology and Medical Intensive Care at the University Medical Center Mannheim, Heidelberg University. Focus: Interventional cardiology with TAVI and mitral valve repair, intensive care with extracorporeal life support, basic research with vascular biology and thrombosis, clinical trials with IITs, HR management with support of young scientists, husband, dad.

Expertise in PE:
Establishment of PERT in Freiburg 2016 and in Mannheim 2021. Pharmacological therapy of high-risk PE since 2004, interventional treatment since 2014. Head of medical intensive care since 2016. Prospective monocentric VTE registry since 2016. Participation in several clinical trials investigating PE management.





Dr. Deepa Gopalan
Deepa Gopalan is the Head of Specialty for Cardiac Imaging at Imperial College London and the Educational Lead for the British Society of Cardiovascular imaging. She is also an Associate Lecturer at Cambridge University, Honorary senior lecturer at Imperial College and Academic Associate at the Karolinska Institute, Stockholm, Sweden. She has published widely on her specialist subjects (Pulmonary Hypertension and Non-invasive Cardiac Imaging) and frequently participates as a speaker at national and international cardiovascular conferences.





Dr. Hobohm
The scientific focus of Dr. Hobohm is on optimizing risk stratification and management strategies for patients with acute pulmonary embolism. In this context Dr. Hobohm also focusing on epidemiological as well as translational "bench-to-bedside" research of thombotic and thromboembolic disorders. Furthermore Dr. Hobohm is working as a senior physician at the Department of Cardiology at the Medical University in Mainz and is supporting as a clinical investigator ongoing prospective cohort studies and interventional trials at the the Center for Thrombosis and Hemostasis (CTH) in Mainz.





Prof. Menno Huisman
Menno Huisman, MD, PhD, FESC, is internist and registrar in cardiovascular medicine and full professor in the Department of Medicine - Thrombosis and Hemostasis at the Leiden University Medical Center.
Dr Huisman's main research areas are in clinical research, particularly in the areas of diagnosis and treatment of venous and arterial thromboembolism.
He is the European representative in the Board of Directors of the United States based PERT organisation.





Dr. Erik Klok
Dr. F.A. (Erik) Klok is a board-certified specialist in Internal Medicine, with a specialty in vascular medicine in the Leiden University Medical Center (Leiden, the Netherlands) and holds a position as visiting professor at the Center for thrombosis and Hemostasis in Mainz (Germany). This allows him to combine clinical work with scientific activities. His research interests include the diagnosis, treatment and long-term complications of venous thromboembolism.





Dr. Adriaan Kraaijeveld
Having received his cardiology training in Leiden, Dr Kraaijeveld is currently an interventional cardiologist at the University Medical Centre Utrecht. Next to structural heart interventions, he has a strong clinical and research interest the invasive treatment of pulmonary embolism, including mechanical support. As such, he serves as one of the coordinating members of the multidisciplinary PE response team.





Prof. Irene Lang
Irene M Lang is a clinical cardiologist and Professor of Vascular Biology at the Medical University of Vienna. She has been nominated as one of the WMA-Caring Physicians of the World in 2005. She directs an out-patient clinic for pulmonary vascular diseases and is an active interventional and structural cardiologist. She also leads basic research on the biology of vascular occlusions, with a special focus on chronic thromboembolic pulmonary hypertension. Prof. Lang is a Member of the Austrian and European societies of cardiology, member of senate of the Medical University of Vienna and Editor for Pulmonary Circulation, the European Heart Journal and Atherosclerosis.





Prof. Nicolas Meneveau
Prof. Nicolas Meneveau is Chief of the Heart-Lung Division and Head of the hemodynamics and interventional cardiology unit at the University Hospital of Besançon (France). He is in charge of venous thromboembolic diseases and has been actively involved in development of guidelines for the management of cardiological emergencies. In his professional career, he has focused extensive work on venous thrombo-embolic disease, particularly on thrombolysis in high risk PE. Professor Meneveau is a member of different professional societies, including the French Society of Cardiology, and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology.





Dr. Lilian Meijboom
Lilian Meijboom is a cardiothoracic radiologist working in the AUMC, Amsterdam, The Netherlands, specialized in pulmonary vascular disease, interstitial lung disease and pulmonary hypertension. She is president of the section Thoracic Radiology of the Dutch Radiology Society and member of the pulmonary embolic rescue team (PERT) in her hospital. The last years she used advanced CTPA and cardiac MRI techniques for early identification of Chronic Tromboembolic Pulmonary Hypertension (CTEPH) patients, better understanding the different phases of pulmonary thromboembolic lesions and evaluating the role of the right ventricle in CTEPH.





Dr. Jose Montero Cabezas
Interventional cardiologist at the Leiden University Medical Center (The Netherlands), with broad experience in complex high-risk coronary procedures, structural heart interventions and mechanical circulatory support in cardiogenic shock. He is co-founder and core member of the local pulmonary embolism response team (ALERT), with focus in invasive therapeutic strategies in patients with pulmonary embolism.





Prof. Fionnuala Ní Ainle
Fionnuala Ní Ainle is a Consultant Haematologist at the Mater Misericordiae University Hospital (MMUH) and Rotunda Maternity Hospital, Dublin, Ireland. She is Full Clinical Professor, University College Dublin (UCD) School of Medicine. She is privileged to treat patients affected with Venous Thromboembolism (VTE) and has a strong interest in women’s issues in thrombosis and haemostasis. Prof. Ní Áinle serves as Director of the Irish Network for VTE Research and with Prof. Patricia Maguire, co-directs the SPHERE Research Group, UCD Conway Institute. She is honoured to work very closely with the Irish patient organization Thrombosis Ireland, raising VTE awareness in Ireland and internationally. She is actively involved in international VTE clinical trials and serves on several trial steering committees. Her translational research interests explore the role of blood coagulation and extracellular vesicles in the aetiology, management and therapy of clinical disorders, particularly disorders of pregnancy. She is a former member of the World Thrombosis Day International Steering Committee and serves as a council member and “director at large” of INVENT-VTE (the International Network of VENous Thromboembolism Clinical Research Networks). She acted as a Section Coordinator on the Task Force of the 2019 European Society of Cardiology (ESC) Guidelines on the diagnosis and management of acute Pulmonary Embolism and serves on the editorial board of several journals, including the Journal of Thrombosis and Haemostasis.





Prof. Piotr Pruszczyk
Head of Dept. of Internal Medicine and Cardiology, Medical University of Warsaw. Main research areas: Assessment of echocardiography and CTPA in diagnosis of acute pulmonary embolism (PE), Role of biomarkers and echocardiography in risk stratification of patients with acute PE, Diagnosis and treatment CTEPH, Cardiovascular complication of musculoskeletal diseases,




   

 

Sponsors


Satellite sessions by our supporting companies

Saturday October 15th, 2022
12.00 -12.30 1st satellite session
15.00 -15.30 2nd satellite session

Sunday October 16th, 2022
10.30 -11.00 3rd satellite session



We thank our sponsors for their unrestricted educational grant.



   

 

Venue & Travel


Stadsgehoorzaal
Breestraat 60
2311 CS Leiden
The Netherlands



Schiphol to Leiden by train

The train journey between Schiphol and Leiden takes about 16 min and covers a distance of around 27 km.
Operated by Dutch Railways (NS), the Schiphol to Leiden train service departs from Schiphol Airport and arrives in Leiden Central. Normally 565 trains run weekly, although weekend and holiday schedules can vary so check in advance.
For more information check: www.ns.nl/reisplanner

   Hotel suggestions

There are several hotels located nearby the Stadsgehoorzaal.

Golden Tulip Leiden Center
www.leiden-centre.goldentulip.com/nl-nl/

Tulip Inn Leiden Centre
www.tulip-inn-leiden-centre.goldentulip.com/nl-nl/

Ibis Leiden Centre
https://all.accor.com/hotel/8087

City Hotel Nieuw Minerva Leiden
www.nieuwminerva.nl/nl/

Hilton Inn Oegstgeest
www.hiltonhotels.com

De Beukenhof Oegstgeest
www.villa-beukenhof.nl


Registration

First come, first served

Registration is accepted according to the 'first come, first served' principle.
Participation is only possible for the two days.

Early bird rate of 275 euros incl. VAT when registering before April 1, 2022.
After April 1, 2022, the registration fee is 325 euros incl. VAT.

Please note: in view of the then current COVID-19 situation, we will adapt the meeting in accordance with restrictions/regulations relevant in October 2022. Your registration will automatically be converted to online if necessary.

You will be redirected via this link to the site of www.bureau-prevents.nl, they take care of the registration.


This symposium is organized by bureau-prevents.




   

 

Contact


Symposium Office:
bureau-prevents
P.O. Box 73
3480 DB Harmelen, the Netherlands
E-mail: info@bureau-prevents.nl